Senior Scientist (Small Molecule Protein)
Cancer Research UK, Blythswood New Town, Glasgow City
Senior Scientist (Small Molecule Protein)
Salary not available. View on company website.
Cancer Research UK, Blythswood New Town, Glasgow City
- Full time
- Permanent
- Onsite working
Posted 1 day ago, 10 Jul | Get your application in today.
Closing date: Closing date not specified
Job ref: ff48a5273bcd40e2b96da13695e77c8b
Location ref: Blythswood New Town, Glasgow City
Full Job Description
- Expression and purification of recombinant proteins using bacterial and insect systems to support screening and crystallography programmes
- Ensure all production is sufficiently characterised and QC'd using appropriate biochemical and biophysical methods
- Interpret, analyse and clearly summarise data for presentation to varied audiences
- Work collaboratively within multi-disciplinary research teams
- Communicate effectively, demonstrating openness and respect for others' perspectives
- Prioritise workload according to project objectives and take responsibility for timely delivery
- Drive scientific and technical innovation, including through internal and external collaborations, while staying current with developments in the field
- Maintain accurate and up-to-date electronic laboratory notebook records
- Take responsibility for assigned laboratory equipment and associated duties
- Uphold safe, compliant and effective working practices
PhD or equivalent in Molecular Sciences, Protein Sciences, Chemistry or significant experience within a drug discovery environment - Significant experience in providing protein production & molecular biology expertise to enable drug discovery projects
- Ability to work in a fast-paced, quickly changing environment, showing agility/flexibility to meet deadlines and goals with a can-do attitude
- Use of current molecular biology techniques (PCR, cloning) to construct expression vectors and isolate genes
- Purification of tagged and native proteins via manual, AKTA and automated purification platforms using a range of chromatographic techniques
- Protein analytical techniques - e.g. protein quantitation assays, SDS-PAGE analysis, HPLC, Western Blotting and protein modifications e.g. biotinylation
- Track record of delivering results across a diverse project portfolio by leading and driving strategic and scientific initiatives Our organisation values are designed to guide all that we do. Bold: Act with ambition, courage and determination Credible: Act with rigour and professionalism Human: Act to have a positive impact on people Together: Act inclusively and collaboratively We're looking for people who can believe in and embody these organisation values and can use them to drive forward progress against our mission to beat cancer.
We have an exciting opportunity for a Senior Scientist in Protein Sciences to join Cancer Research Horizons in our Glasgow lab. You'll lead the expression, purification and QC of protein antigens and related molecules (small molecule drug discovery focus), all of which play a critical role in driving our screening and crystallography programmes. Working primarily across bacterial and insect systems, you'll deliver high quality, well characterised proteins using a range of biochemical and biophysical methods. You'll collaborate closely with multidisciplinary drug discovery teams, communicate insights clearly, drive strategic decisions, innovate across the existing pipeline, bring strong scientific leadership the team, and help ensure a safe, efficient lab environment. You'll collaborate closely with multi-disciplinary teams, communicate insights clearly, maintain high-quality electronic records and help ensure a safe, efficient lab environment. We're looking for candidates with a PhD (or equivalent experience) in Molecular/Protein Sciences, Chemistry with substantial drug discovery experience, with strong protein production and molecular biology expertise. This is a high impact role that advances our discoveries. If you're adaptable, driven, and ready to make a scientific impact, this is your chance to contribute. Every role at CRH is united by a single mission: beating cancer sooner. We carry out work that matters - impacting patients, families, and the future of science.-discovery experience, with strong molecular biology, protein purification-based expertise. About Cancer Research Horizons As the world's biggest medical research charity, we've helped bring eleven new cancer drugs to market. However, there is still an urgent need to bring more effective treatments to patients faster. We have recently developed a new approach to driving therapeutic innovation through the creation of Cancer Research Horizons (CRH). We have brought together Cancer Research UK's established drug discovery teams under one organisation and leadership team, combining our unique pipeline of cancer biology expertise and access to CRUK's world-class academic network, cutting edge technology platforms and clinical expertise to 1) Bring new treatments to patients faster and 2) Tackle the biggest challenges in discovering cancer drugs by seeking out more radical ideas and embracing risk in our bid to achieve success. Based at sites in Cambridge, the CRUK Scotland Institute in Glasgow, and Newcastle University, you'll be joining over 200 staff from both industrial and academic backgrounds, all dedicated to bringing forward the day we cure cancer.
Direct job link
https://www.s1jobs.com/job/senior-scientist-small-molecule-protein-127097041